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Faculty Profile

 

Prof. Indu Bhusan Chatterjee
D.Sc, FNA

INSA Honorary Scientist & Joint Coordinator, GCGEB, Calcutta University

Email:ibc123@rediffmail.com

  Educational Qualification

B.Sc (Hons) Chemistry – Scottish Church College, Calcutta University

M.Sc (Applied Chemistry) – Calcutta University

D.Sc (Applied Chemistry) – Calcutta University

  Important Publications
1. Misra, A., Chattopadhyay, R., Banerjee, S., Chattopadhyay, D. J. and Chatterjee, I.B. Black tea prevents cigarette smoke induced oxidative damage of proteins in guinea pigs. J. Nutrition, 133, 2622-2628 (2003).(Impact Factor – 3.69)

2. Banerjee, S., Misra, A., Chattopadhyay, D. J., and Chatterjee, I. B. Black tea as an antidote for cigarette smoke-induced oxidative damage of proteins. In Medical Properties of Tea, Eds. B. Banerjee and T. C. Choudhuri, pp.113-131 (Oxford & IBH Publishing Co. Pvt. Ltd., 2005).

3. Failure of Alpha-Tocopherol to Prevent Cigarette Smoke-Induced Protein Oxidation: Comparison with Other Antioxidant Vitamins. Panda K. and Chatterjee I.B. Encyclopedia of Vitamin E. Oxford University Press (CABI), Oxordshire, UK. Editor, Victor R. Preedy,Kings College, London, UK. Chapter 63.p-883-893 (2007).

4. Banerjee, S., Maity, P., Mukherjee, S., Sil, A. K., Panda, K., Chattopadhyay, D., and Chatterje, I. B. Black tea prevents cigarette smoke-induced apoptosis and lung damage. J. Inflammation (London) 4, 3 (2007). (Impact Factor- 3.19)

5. Chatterjee I. B. and Dey N. Regarding detection of hydrogen peroxide in cigarette smoke. The FASEB Journal, Letters to the Editor 22:3755 (2008).(Impact Factor – 6.63)

7 Banerjee S., Chattopadhyay R., Ghosh A., Koley H., Panda K., Roy S., Chattopadhyay D. and Chatterjee I. B., Cellular and molecular mechanisms of cigarette smoke-induced lung damage and prevention by vitamin C, J. Inflammation 5:21 (2008). (Impact Factor- 3.19)

8. Chatterjee, I. B., B. C. Guha: The doyen of Indian biochemists and pioneer of vitamin C research, Science and Culture 75: 29-33 (2009)

9. Chatterjee, I. B., Evolutionary loss of vitamin C synthesizing ability in terrestrial vertebrates, Science and Culture 75: 113-119 (2009)

10. Chatterjee, I. B., The history of vitamin C research in India, J. Biosciences in press (2009).


  Research interests

1. Cellular and molecular mechanisms of cigarette smoke-induced emphysema p-Benzosemiquinone a long-lived radical of cigarette smoke, through formation of p-benzoquinone, produces protein modification, apoptosis and emphysematous lung damage in a guinea pig model developed in our laboratory.

 

2. Role of NADPH-quinone oxidoreductase and vitamin C deficiency on cigarette smoke/p-benzoquinone-inducedmyelodystrophic syndrome.

 

 

3. p-benzoquinone-induced alteration of structure and function of human serum albumin.

4. p-benzoquinone-induced histone modification and epigenetic regulation of gene expression.

    

  Patents Granted

Patent # 1

 Process for the isolation of a major harmful oxidant from cigarette smoke

 Inventor: Indu Bhusan Chatterjee

Assignee: CSIR

1.  United States Patent No. 6,929,012, dated August 16, 2005
2.  Korea: Patent No. 10-0868687, dated November 7, 2008
3. Japan:    Patent No. 4094545, dated March 13, 2008

Patent # 2

Activated charcoal filter for effectively reducing p-benzosemiquinone from the mainstream cigarette smoke

Inventor: Indu Bhusan Chatterjee

Assignee: CSIR

1. United States Patent No. 7,025,067 B2, dated April 11, 2006
2. Japan: Patent No. 3966856, dated August 29, 2008
3. Europe (EP):   Patent No. EP1434503, dated May 7, 2008 (Validated in UK, Italy, France, Spain,Germany, Portugal and Greece)

 

  Lab Members

Archita Das

Phularenu Guha Research Fellow

archita_cu@rediffmail.com

Neekkan Dey

Juthika Research Fellow

neekkandey@gmail.com

Arunava Ghosh

Senior research fellow (PhD student)

arunavag@ymail.com

 

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